- Dbl family
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(= Dbl, Dbs, Brx, Lfc, Lsc, Ect2, DRhoGEF2, Vav)Family of proteins containing DH domains and with guanine nucleotide exchange factor activity for rho family of small G-proteins.
Dictionary of molecular biology. 2004.
Dbl family
Look at other dictionaries:
dbl — Human oncogene originally identified by transfection of NIH 3T3 cells with DNA from human diffuse B cell lymphoma. A guanine nucleotide exchange factor (GEF) for rho family members. Protein contains a domain of around 250 amino acids, the Dbl… … Dictionary of molecular biology
DH domain — (= Dbl homology domain) Domain of around 250 amino acids found in Dbl, Vav and a family of other Dbl family proteins (Lfc, Lsc, Ect2, Dbs, Brx). DH domains are invariably located immediately N terminal to PH domain and the membrane localization… … Dictionary of molecular biology
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Guanine nucleotide exchange factor — Guanine nucleotide exchange factors (GEFs) are components of intracellular signalling networks. They function as activators of small GTPases (see Nucleotide exchange factor). In their resting state, G proteins are bound to Guanosine diphosphate… … Wikipedia
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VAV1 — Vav 1 oncogene, also known as VAV1, is a human gene. PBB Summary section title = summary text = The protein encoded by this proto oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP… … Wikipedia
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ARHGEF12 — Rho guanine nucleotide exchange factor (GEF) 12, also known as ARHGEF12, is a human gene.cite web | title = Entrez Gene: ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… … Wikipedia
